Protect gently go Zero

Discover Perio plus zero – Crafted with care and trusted by professionals.

Gentle care, powerful protection

Curaprox Perio plus zero was developed to meet the highest standards in patient care. Its next-generation formula removes CHX, offering advanced antibacterial effectiveness, long-lasting substantivity, and zero side effects. Ideal for a wide range of dental cases, it’s proven and tested by dental professionals to provide protection against plaque build-up while maintaining the balance of the oral microbiome.

Experience superior effectiveness and gentleness.

Zero CHX, Zero Compromises, Zero Side Effects

  • Patented Citrox®/P-Complex
  • Antimicrobial properties
  • Extended protection
  • Balanced microbiome
  • Pleasant taste
  • Non-staining formula
  • Long-lasting substantivity
  • Free from chlorhexidine, alcohol, triclosan, and SLS

Your opinion, our priority

Proven Efficacy: In Vitro Studies

Antibacterial effect of Perio plus zero against Streptococcus mutans
The study demonstrates that Zero effectively targets Streptococcus mutans, showing good antibacterial effectiveness and superior substantivity.

Effective against key oral pathogens

Perio plus zero remains effective even when diluted, targeting:

  • Porphyromonas gingivalis, an important pathogen that causes periodontal disease
  • Streptococcus mutans, a bacterium that causes caries
  • Solobacterium moorei, a bacterium associated with halitosis

The Next-Gen formula

Stop the bad… protect the good.

Frequently asked Questions

Perio plus zero offers effective antibacterial protection while keeping the microbiome balanced. It targets harmful bacteria without affecting the good ones. The formula is CHX-free, alcohol-free, and SLS-free, making it gentle and effective. It’s safe for long-term use and can be used before, during, or after treatment.


Unlike many mouthwashes that eliminate both harmful and beneficial bacteria, Perio plus zero is microbiome-friendly, preserving the beneficial bacteria in the mouth. It avoids the common issues of alcohol-based formulas, which can cause dryness and irritation, and CHX, which is associated with staining and alters the taste. Additionally, Perio plus zero features a specialized formula that targets pathogens and bacteria responsible for periodontal disease, caries, and halitosis. These benefits are supported by clinical approval conducted by dental professionals and in vitro studies.


Perio plus zero is suitable for adults, the elderly, and children aged 6 and above (once they can control swallowing). It is perfect for individuals dealing with gum issues, dry mouth, or bad breath. It is also recommended for use during orthodontic treatment to help maintain oral hygiene and prevent related concerns.


Perio plus zero has a safe pH range between 6.0 and 7.5. This means there is no risk of acid erosion on enamel.


Perio plus zero is suitable for both short-term and long-term use, depending on individual needs. It is not required for daily use, so its usage can be adjusted based on specific oral health concerns (such as gum issues, dry mouth, or bad breath) and recommendations from a dentist.


Perio plus zero is recommended for a wide range of cases, including:

  • Gum problems
  • Halitosis (bad breath)
  • Dry mouth
  • During orthodontic treatment


Perio plus zero is both bacteriostatic and bactericidal. Stops bacterial growth and eliminates harmful strains.


While Perio plus zero is suitable for use with any toothpaste, it is generally not recommended to use toothpastes containing Sodium Lauryl Sulfate (SLS), as SLS can cause irritation and disrupt the oral microbiome. For the best results, choose toothpastes that are gentle.


First, shake the bottle well. Rinse 10ml undiluted for at least 60 seconds, twice daily, ideally after brushing your teeth. For best results, wait at least 30 minutes after brushing before using.

For children (6 years and older): Use up to 5ml of the mouthwash, and dilute it with drinking water to make a total of 10ml. This will reduce the intensity of the flavor. Rinse with the diluted solution for 2 minutes.